gene therapy hearing loss treatment otonomy

Otonomy and AGTC Present Preclinical Results for GJB2 Gene Therapy Hearing Loss Program

SAN DIEGO, CALIFORNIA — Otonomy, Inc., a biopharmaceutical company dedicated to the development of innovative therapeutics for neurotology, today announced preclinical results from the company’s gene therapy collaboration with Applied Genetic Technologies Corporation (AGTC) that support the selection of a product candidate for development as a treatment for gap junction beta-2 (GJB2) deficiency, the most…

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usher syndrome treatment

Research Suggests Potential of In-Womb Gene Correction for Some Genetic Hearing Disorders

PORTLAND, OREGON — New research led by hearing scientists at Oregon Health & Science University (OHSU) suggests an avenue to treat and prevent intractable genetic disorders before birth. Researchers at the Oregon Hearing Research Center at OHSU, working with mice, injected a specially designed synthetic molecule into the developing inner ear of fetal mice 12…

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age related hearing loss genes identified

UK Researchers Identify 44 Genes Tied to Age-Related Hearing Loss, Raising Hope for Future Treatment Options

LONDON, UNITED KINGDOM — Researchers from King’s College London, and University College London (UCL), have identified 44 genes linked to age-related hearing loss. The study helps shed light and provide a much clearer understanding of how the condition develops, and also potential treatment options in the future. The study, published in The American Journal of…

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gene therapy for hearing loss

Akouos Discloses Lead Program, AK-OTOF, a Potential Gene Therapy Treatment for Sensorineural Hearing Loss

BOSTON, MASS. – Akouos, a precision genetic medicine company developing gene therapies to restore and preserve hearing, today disclosed its lead program, AK-OTOF, a gene therapy focused on restoring hearing in individuals with sensorineural hearing loss due to mutations in the otoferlin (OTOF) gene. Normal otoferlin function enables the sensory cells of the ear (hair…

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