UVA Researchers Find Essential Key to Hearing Sensitivity Within the Inner Ear

CHARLOTTESVILLE, VIRGINIA — New research from the University of Virginia School of Medicine is helping shed light on the biological architecture that lets us hear – and on a genetic disorder that causes both deafness and blindness. Sihan Li, a graduate student in the lab of Jung-Bum Shin of UVA’s Department of Neuroscience, has made a surprising…

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gene therapy hearing loss treatment otonomy

Otonomy and AGTC Present Preclinical Results for GJB2 Gene Therapy Hearing Loss Program

SAN DIEGO, CALIFORNIA — Otonomy, Inc., a biopharmaceutical company dedicated to the development of innovative therapeutics for neurotology, today announced preclinical results from the company’s gene therapy collaboration with Applied Genetic Technologies Corporation (AGTC) that support the selection of a product candidate for development as a treatment for gap junction beta-2 (GJB2) deficiency, the most…

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usher syndrome treatment

Research Suggests Potential of In-Womb Gene Correction for Some Genetic Hearing Disorders

PORTLAND, OREGON — New research led by hearing scientists at Oregon Health & Science University (OHSU) suggests an avenue to treat and prevent intractable genetic disorders before birth. Researchers at the Oregon Hearing Research Center at OHSU, working with mice, injected a specially designed synthetic molecule into the developing inner ear of fetal mice 12…

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Gene Therapy Expert, Dr. Géraldine Honnet, Appointed as Sensorion’s New Chief Medical Officer

MONTPELLIER, FRANCE — Sensorion, a clinical-stage biotech company which specializes in the development of novel therapies to restore, treat and prevent within the field of hearing loss disorders, has announced the appointment of gene therapy expert Géraldine Honnet MD, as Chief Medical Officer.  Géraldine Honnet is a medical doctor and joins from Généthon, where she…

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age related hearing loss genes identified

UK Researchers Identify 44 Genes Tied to Age-Related Hearing Loss, Raising Hope for Future Treatment Options

LONDON, UNITED KINGDOM — Researchers from King’s College London, and University College London (UCL), have identified 44 genes linked to age-related hearing loss. The study helps shed light and provide a much clearer understanding of how the condition develops, and also potential treatment options in the future. The study, published in The American Journal of…

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sensorion gene therapy hearing loss

Sensorion Announces Partnership Framework Agreement with Institut Pasteur on Gene Therapy Programs for Hearing Loss

MONTPELLIER, FRANCE — French biotech firm Sensorion has announced the signature of a research partnership framework agreement with Institut Pasteur (Paris) granting to Sensorion an option to obtain exclusive licenses to develop and market drug candidates in gene therapy coming from collaborative projects, for the restoration, treatment and prevention of hearing disorders. In accordance with…

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genetic hearing loss research

University of Miami Receives $3M NIH Grant for Genetic Hearing Loss Research

MIAMI, FLORIDA — The University of Miami Miller School of Medicine Department of Otolaryngology has received a $3 million grant from the National Institutes of Health (NIH) that will fund research related to biological treatments and clinical diagnosis of patients with hearing loss. The grant allows Xue Zhong Liu, M.D., Ph.D., professor of otolaryngology, human…

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hearing loss genetics

Israeli Researchers Get One Step Closer to Unraveling Cause of Human Deafness

As much as 98% of the human genome does not code for protein. RNAs contained in this non-coding part act as regulatory molecules and have a substantial impact on gene expression. One type of these RNA molecules, called long non-coding RNAs, has been linked to a wide range of diseases and inheritable conditions such as…

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