inner ear hair cells

Reprogramming Inner Ear to Regrow Lost Hair Cells? New Discovery Holds Promise for Future Hearing Loss Treatments

BOSTON, MASSACHUSETTS — A new discovery from a team led by Massachusetts Eye and Ear researchers may bring scientists a step closer to developing treatments that regrow the missing cells that cause hearing loss. In a new study, published online December 4, 2019, in Nature Communications, scientists report a new strategy to induce cell division in the…

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hair cell regeneration hearing loss therapy

Researchers Find Proteins That May Hold Key to Restoring Inner Ear Hair Cells

BALTIMORE, MARYLAND —  Researchers at Johns Hopkins Medicine, report that they have identified a pair of proteins that precisely control when hair cells (sound detecting cells) are born in the mammalian inner ear. The proteins, described in a report published June 12 in eLife, may hold a key to future therapies to restore hearing in…

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frequency therapeutics financing development fx-322

Frequency Therapeutics Raises $62 Million in Latest Financing Round to Support Hearing Loss Drug Development

WOBURN, MASSACHUSSETTS — Frequency Therapeutics, a clinical-stage biotechnology company focused on harnessing the body’s innate biology to repair or reverse damage caused by a broad range of degenerative diseases, today announced the closing of a $62.0 million Series C financing. Frequency will use the proceeds to support the clinical development of FX-322, a regenerative therapeutic…

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vestibular hair cell regeneration

Researchers Regenerate Hair Cells in Vestibular System of Mice

Researchers at the Stanford University School of Medicine have found a way to regenerate hair cells in the inner ears of mice, allowing the animals to recover vestibular function. This is the first time such recovery has been observed in mature mammals. The research was published recently published on July 9 in Cell Reports. According to the…

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New Trial Raising Hope for Development of First Drug to Restore Hearing

LONDON, UNITED KINGDOM — Researchers at UCLH’s Royal National Throat Nose and Ear Hospital (RNTNEH) and UCL Ear Institute are leading a drug trial aimed at regenerating the sensory receptors (hair cells) in the inner ear. While long thought to be irreversible, past animal studies have indicated that these cells can be regenerated through the…

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hearing loss restoration study

Study Points to Possible New Therapy Approach for Hearing Loss Treatment

ROCHESTER, NEW YORK — In a new study published this week in the European Journal of Neuroscience, scientists have been able to regrow the sensory hair cells found in the cochlea. The research may help pave the way for new approaches to restoring lost hearing. Research conducted in the lab of Patricia White, Ph.D., lead author of…

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cochlea hair cell restoration

Cochlear Architecture Critical Part of Hair Cell Regeneration

The ability to restore hearing by regenerating outer hair cells in the cochlea of the inner ear, sometimes referred to as biological solutions for hearing loss, has shown success in restoring hearing sensitivity in animal studies. New research, however, indicates that restoring hearing is more than regenerating lost or damaged outer hair cells. In a…

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acousia therapeutics hearing loss drug

Acousia Therapeutics Receives €10 Million Investment to Advance Pipeline of Preclinical Hearing Loss Drug Candidates

TÜBINGEN, GERMANY — Acousia Therapeutics, a privately held biotech firm developing novel therapies for inner ear disease and pathologies, announced this week the closing of a €10 million (approximately $11.8M USD) Series B financing round to “advance its pipeline of preclinical drug candidates into clinical stage”.  According to the announcement, the financing round was led…

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hearing loss restoration rna injection

Scientists Regenerate Cochlear Hair Cells in Guinea Pigs Using RNA Injection

The cochlear hair cells of humans and other mammals–unlike some animal species (like birds for example)–cannot be restored after damage. Recent research has indicated, however, that manipulation of signaling pathways could lead to hair cell regeneration. Using a sustained-release formulation of small interfering RNAs (siRNAs) delivered via nanoparticles into the cochlea of noise-injured guinea pigs,…

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akouos gene therapy hearing loss treatment

Boston-Based Biotech, Akouos, Nets $7.5M Investment to “Restore and Preserve Hearing”

BOSTON, MASSACHUSETTS — Biotechnology startup, Akouos, announced that it has raised $7.5 million in seed funding. The company, which was spun out of the Harvard Innovation Labs, is developing novel therapies and delivery systems to prevent hearing loss and restore hearing in genetically defined populations. New Enterprise Associates (NEA), who led the seed funding along…

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