Researcher Receives $1.8M to Study Effect of Hormones on Hearing Loss

A University of Iowa biologist has received funding from the National Institutes of Health to further investigate how a hormone may prevent hearing loss in humans. Steven Green will continue his research into how responses to progesterone will lead to therapeutics for repairing damage to the inner ear caused by noise. Previous research has shown that…

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A Combination of Sound and Silence May Help Slow the Progression Hearing Loss

Researchers at the University of Rochester Medical Center have found intermittent broadband sound played over an extended period of time preserved sensory cells in the ear, while also rewiring some of the central auditory system in the brain, helping preserve the ability to sense the timing of sounds. “By showing that the detection of sound…

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Researchers Develop First 3D Sound Frequency Map of Inner Ear Using Advanced X-Ray Technology

Researchers at Uppsala University have created the first 3D map of the hearing nerve showing where the various sound frequencies are captured. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ, the cochlea, and find out exactly how the frequencies of incoming…

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New Research Helps Shed light on How Hearing Happens at the Molecular Level

We hear sounds in part because tiny filaments inside our inner ears help convert voices, music and noises into electrical signals that are sent to our brains for processing. Now, scientists have mapped and simulated those filaments at the atomic level, a discovery that shed lights on how the inner ear works and that could…

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pipeline therapeutics hearing loss treatment pipe-505

Pipeline Therapeutics Initiates Phase 1/2a Clinical Trial of PIPE-505 to Treat Sensorineural Hearing Loss

SAN DIEGO, CALIFORNIA –Pipeline Therapeutics, a biopharmaceutical company focused on the development and commercialization of first-in-class small molecules for neuroregeneration, today announced the initiation of a Phase 1/2a trial of the company’s lead product candidate, PIPE-505, a small molecule gamma secretase inhibitor (GSI), in sensorineural hearing loss (SNHL) associated with hearing speech in noisy environments.…

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sense hearing end of life

Research Finds Sense of Hearing Persists at End of Life

Hearing is widely thought to be the last sense to go in the dying process. Now University of British Columbia (UBC) researchers have evidence that some people may still be able to hear while in an unresponsive state at the end of their life. This research, published recently in Scientific Reports, is the first to investigate…

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New Study Charts Developmental Map of Inner Ear Sound Sensor in Mice

BETHESDA, MARYLAND — A team of researchers has generated a developmental map of a key sound-sensing structure in the mouse inner ear. Scientists at the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health, and their collaborators analyzed data from 30,000 cells from mouse cochlea, the snail-shaped structure…

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cochlear blood vessels

Researchers Use Advanced 3D Imaging to Map Blood Vessels of the Inner Ear

Swedish and Canadian researchers have used an advanced 3D imaging technique, synchrotron X-rays, to three-dimensionally map the blood vessels of the inner ear. To be able to study the blood vessels in the inner auditory organ, the researchers used the synchrotron system in Saskatoon, Saskatchewan, Canada. The system, which is one of eight in the…

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kavli prize inner ear

Prestigious Kavli Prize in Neuroscience Awarded to Trio of Researchers for Work on Molecular and Neural Mechanisms of Hearing

OSLO, NORWAY — The Kavli Prizes recognize scientists for pioneering advances and are presented every two years in the fields of astrophysics, nanoscience and neuroscience. Laureates are chosen by committees whose members are recommended by six of the world’s most renowned science societies and academies. This year, a trio of scientists have been awarded the 2018…

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