New Israeli Study Suggests COVID-19 Does Not Damage Auditory System

December 15, 2020

Since the beginning of the COVID-19 pandemic, there have been reports in the professional literature on possible hearing loss caused by the disease. A new study from Tel Aviv University (TAU), in collaboration with the Galilee Medical Center, finds no evidence of damage to the auditory system as a result of COVID-19 infection.

The findings seemingly run contrary to a number of case reports and speculation in the professional literature over the past several months regarding hearing loss and COVID-19 infection. A recent survey of audiologists in the US found that approximately 15% of respondents said they have personally encountered a patient reporting hearing loss as a result of COVID-19 infection.

The study was led by Professor Karen Avraham of TAU’s Sackler Faculty of Medicine. The results were published online in the journal Otology & Neurotology on December 8, 2020.

“Since the beginning of the pandemic, it has been clear that COVID-19 has some long-term effects, such as the loss of the sense of smell and taste. The possibility of hearing loss, however, has been debated among medical practitioners, with some reporting this symptom in recovered patients. The question is whether such hearing loss is caused by damage to the auditory system, or whether it is a temporary symptom caused by fluids clogging the middle ear, as often happens with a common cold.”

–Prof. Karen Avraham

The researchers began to investigate this question during the first wave of the pandemic, when the numbers of patients in Israel were still relatively small.  Participants included eight asymptomatic individuals who had tested positive for COVID-19 and eight healthy volunteers who served as a control group, none of whom reported any previous hearing loss.

According to the researchers, the study “provided for the first time quantitative measures for hearing quality” following exposure to the virus.


COVID-19 and Hearing Symptoms


“Our study explored whether COVID-19 can cause permanent neural or sensory damage to the hearing system. We found no evidence for such damage,” says co-author Dr. Amiel Dror of the Galilee Medical Center and the Azrieli Faculty of Medicine at Bar-Ilan University. “We measured electrical data from the brainstem to test the entire route of soundwaves through the ear until electric waves are ultimately received in the brain. We also examined the activity of the inner ear hair cells that intensify and tune the sound. We found no difference between the COVID-19-positive subjects and the control group.”

“It’s true that at this initial stage the study examined asymptomatic patients,” Professor Avraham continues. “But objective scientific research takes a long time, and we started recruiting our volunteers in April, at the peak of the first wave pf the pandemic in Israel. There are so many speculations about this virus and the damage inflicted by it, and we have shown that at least in the auditory system no damage was detected.”

“It’s very important to base our knowledge of the virus upon objective studies and refrain from hasty conclusions,” says Dr. Dror. “The social media have attributed numerous illnesses and symptoms to the coronavirus, but often the information is unfounded and leads to unwarranted stress, as well as needless pressure on the health system.”

“This study proposes that the COVID virus does not cause extensive neurological damage but is rather spotty, mostly affecting the sense of smell. Moreover, the hearing impairment among some patients is mostly transient and secondary to fluid buildup in the middle ear, as for the common cold, and therefore likely passes once the acute disease is over.”

–Co-author Dr. Eyal Sela, Galilee Medical Center and Azrieli Faculty of Medicine at Bar-Ilan University

The researchers are currently conducting a much more comprehensive study with hundreds of patients, including persons who had been severely ill and even ventilated.



Amiel A. Dror, Najla Kassis-Karayanni, Adi Oved, Amani Daoud, Netanel Eisenbach, Matti Mizrachi, Doaa Rayan, Shawky Francis, Eli Layous, Yoni Evgeni Gutkovich, Shahar Taiber, Samer Srouji, Shai Chordekar, Sonia Goldenstein, Yael Ziv, Ohad Ronen, Maayan Gruber, Karen B. Avraham, Eyal Sela. Auditory Performance in Recovered SARS-COV-2 PatientsOtology & Neurotology, 2020; Publish Ahead of Print DOI: 10.1097/MAO.0000000000003037



Tel Aviv University (TAU) exemplifies the qualities of the city it inhabits — innovative, fast-paced, exciting, and creative. A globally top-ranked university, a leading research institution, a center of discovery — TAU embraces a culture and student body that is inquisitive and responsive to pressing issues and world-wide problems. As Israel’s largest public institution of higher learning, TAU is home to 30,000 students, including 2,100 international students from over 100 countries. The University encompasses nine faculties, 35 schools, 400 labs, and has 17 affiliated hospitals in its network.


Source: TAU, Otology & Neurology

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